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The purpose of this systematic review was to compare corticosteroid injections with non-steroidal anti-inflammatory drug (NSAID) injections for musculoskeletal painwith a view to estimating the effect on safety with a more appropriate population in both settings. We searched the electronic databases of Cochrane Central Register of Controlled Trials (CENTRAL), Embase and Cochrane Central Register of Controlled Trials (CENTR). Medline and Spine were searched for articles published between 1 January 1990 and 1 March 2012, steroids online reviews uk. Studies were included if there was any evidence of an effect on pain, safety and adverse effects. We considered any study published before 1 April 2011 as an observational study, which is the start of the meta-analysis period, steroids online reviews uk. We excluded studies that reported more than one type of treatment if the primary aim was to improve pain and no difference in pain was found, steroid-pharm review. RESULTS: More than 200 articles were found, of which 30 studies met the inclusion criteria, steroids online forum. Of the studies, 20 showed a significant effect of corticosteroid injections on pain in both settings. A systematic review of trials (Cochrane review) showing an effect on pain was also carried out but found no improvement in pain due to NSAIDs, steroids online uk forum. No effect was found in a pooled analysis of randomised controlled trials (RCTs) that reported effect on pain by comparing corticosteroids with placebo (RCTs) or corticosteroids with no treatment. There was no difference between the outcomes in those studies that had adjusted for age and in those studies that used a blinded randomised design. There was no difference between the outcomes of trials in which the primary focus was on NSAID users and those in which the primary focus was on corticosteroids, review steroid-pharm. CONCLUSIONS: We concluded that no difference in pain was found for corticosteroid injections when compared to non-steroidal anti-inflammatory drugs (NSAIDs) or placebo. However, this was at odds with a systematic review that suggested there was an effect of corticosteroid injections on pain, steroids online philippines. We also argued for more study into long-term side effects, steroids online uk forum.
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